Hypersensitivity to glucorticoids in children
نویسندگان
چکیده
Methods We present 8 children with suspected hypersensitivity reaction after parenteral MP (6 children), DX inhalation (1 child) and inhafluticasone propionate (FL) (1 child). Prick and intradermal skin testing with MP, HC, DX and FL were performed. In case of negative skin tests provocation tests were performed. Basophil activation test (flow cytometry analyses of basophil CD63 surface expression induced by different concentrations of MP, HC, DX and FL (333, 33,3 and 3,33 mcg/ml)) was performed in all patients and in ten controls who tolerated those drugs. Stimulation index (SI) >2 was considered positive.
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